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Protein-protein interactions

Protein-protein interactions

Adressing the interactome with PPI assays

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6His Check kit Gold

HTRF® Kit

The 6His check kit Gold enables the rapid detection of 6His tagged fusion proteins.

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APP (BACE1 substrate)

HTRF® Other reagent

APP substrate is used in the case of High enzymatic Km to monitor beta-secretase (BACE1) activity.

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Protein Degradation

Accelerated solutions for targeted protein degradation and drug discovery

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Biotin-APP-Eu cryptate (BACE1 substrate)

HTRF® Other reagent

APP substrate is labeled with both biotin and Eu3+ Cryptate and used to monitor human beta-secretase...

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Biotin-Heparan sulfate-Eu cryptate reagent

HTRF® Fluorescent reagent

A proprietary heparan sulfate substrate labeled with both biotin and Eu3+ Cryptate to monitor hepara...

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Cereblon binding kit

HTRF® Kit

The Cereblon binding assay is designed to screen and characterize compounds that specifically bin...

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Technical Notes

Best practices for pharmacological characterization of PPI i...

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Cereblon Standard

HTRF® Standard

Cereblon Standard is intended for use with the Cereblon binding kit.

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d2 Labeling kit

HTRF® Kit

d2 labeling kit tailored for biomolecule labeling and straightforward development of time-resolved f...

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Diluent 9 (5x)

HTRF® Buffer

Diluent #9 is intended for the proper preparation and dilution of compound prior to qualification...

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DNP-NHS labeling reagent

HTRF® Other reagent

DNP-NHS labeling reagent enables DNP labeling of biomolecules.

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Europium cryptate Labeling kit

HTRF® Kit

Europium cryptate labeling kit tailored for biomolecule labeling and straightforward development of ...

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Europium cryptate TBP maleimide labeling reagent

HTRF® Other reagent

Europium cryptate TBP maleimide labeling reagent enables Europium cryptate labeling of biomolecules.

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Europium cryptate TBP NHS labeling reagent

HTRF® Other reagent

Europium cryptate TBP NHS labeling reagent enables Europium cryptate labeling of biomolecules.

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Autoimmune diseases

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Europium cryptate-NH2 labeling reagent

HTRF® Other reagent

Europium cryptate-NH2 labeling reagent enables Europium cryptate labeling of biomolecules.

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Flag Check kit

HTRF® Kit

The Flag Check kit enables the rapid detection of Flag tagged fusion proteins.

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FLAG check kit standard

HTRF® Standard

FLAG spare standard intented for use in the Flag Check kit.

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Application Notes

HTRF assays handle low- to high affinity protein-protein int...

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GST check kit

HTRF® Kit

The GST check kit enables the rapid detection of GST tagged fusion proteins.

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GST check kit standard

HTRF® Standard

GST spare standard intented for use in the GST check kit.

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HTRF cIAP1 BIR2 Binding Kit

HTRF® Kit

The cIAP1 BIR2 Binding Kit is designed to identify, characterize, and profile compounds...

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HTRF cIAP1 BIR2 Binding Kit - Standard

HTRF® Standard

cIAP1 BIR2 Standard is intended for use with the HTRF cIAP1 BIR2 binding kit.

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HTRF cIAP1 BIR3 Binding Kit

HTRF® Kit

The cIAP1 BIR3 Binding Kit is designed to identify, characterize, and pr...

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HTRF cIAP1 BIR3 Binding Kit - Standard

HTRF® Standard

cIAP1 BIR3 Standard is intended for use with the HTRF cIAP1 BIR3 binding kit and LCL-161 Red Liga...

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HTRF Human RIG-I Binding Kit

HTRF® Kit

The human RIG-I binding assay is designed to select and characterize compounds that spe...

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Protein Degradation

Accelerated solutions for targeted protein degradation and drug discovery

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HTRF Human RIG-I Binding Kit Standard

HTRF® Standard

HTRF® Human RIG-I Binding Kit Standard is intended for use with the Human RIG-I bindin...

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HTRF Human VHL Binding Kit

HTRF® Kit

The VHL binding assay is designed to screen and characterize compounds that specifically bind to the...

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HTRF Human VHL Binding Kit Standard

HTRF® Standard

The VHL Standard is intended for use with the HTRF Human VHL binding kit and VHL-Red Ligand.

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Application Notes

Nuclear receptor ligand identification with HTRF

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HTRF LCL161 - Red Ligand

HTRF® Fluorescent reagent

HTRF LCL161-Red Ligand can be used for affinity binding experiments in association with the HTRF ...

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HTRF MDM2 Binding Kit

HTRF® Kit

The MDM2 binding assay is designed to screen and characterize compounds that specifically bind to...

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HTRF MDM2 Binding Kit - Standard

HTRF® Standard

MDM2 Standard is intended for use with the HTRF MDM2 binding kit and MI-1061 Red Ligand.

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HTRF MI-1061 Red Ligand

HTRF® Fluorescent reagent

HTRF MI-1061 Red ligand is a derivative of MI-1061 and can be used as a fluorescent tracer for HT...

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HTRF PROTAC Binding Buffer 1 - 200mL

HTRF®

HTRF PROTAC Binding Buffer 1 is a spare part intended for use in biochemical E3 l...

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HTRF PROTAC Binding Buffer 2-220mL

HTRF®

HTRF PROTAC Binding Buffer 2 is a spare part intended for use in biochemical...

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HTRF PROTAC Binding Buffer 3-220mL

HTRF®

HTRF PROTAC Binding Buffer 3 is a spare part intended for use in biochemical E3 ligase binding...

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Autoimmune diseases

A world to explore

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HTRF Strep-Tactin®-d2

HTRF® Fluorescent reagent

HTRF Strep-Tactin®-d2 can be used to capture Strep-tag® II and Twin Strep-tag®-tagge...

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HTRF Strep-Tactin®-Eu cryptate

HTRF® Fluorescent reagent

HTRF Strep-Tactin®-Eu cryptate can be used to capture Strep-tag® II and Twin Strep-tag®-t...

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HTRF Strep-Tactin®-Tb cryptate

HTRF® Fluorescent reagent

HTRF Strep-Tactin®-Tb cryptate can be used to capture Strep-tag® II and Twin Strep-tag®-t...

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Application Notes

Harness avidity without compromising on pharmacology

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HTRF Strep-Tactin®-XL665

HTRF® Fluorescent reagent

HTRF Strep-Tactin®-XL665 can be used to capture Strep-tag® II and Twin Strep-tag®-ta...

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Protein-protein interactions

Adressing the interactome with PPI assays

6His Check kit Gold

APP (BACE1 substrate)

Biotin-APP-Eu cryptate (BACE1 substrate)

Biotin-Heparan sulfate-Eu cryptate reagent

Cereblon binding kit

Cereblon Standard

d2 Labeling kit

Diluent 9 (5x)

DNP-NHS labeling reagent

Europium cryptate Labeling kit

Europium cryptate TBP maleimide labeling reagent

Europium cryptate TBP NHS labeling reagent

Europium cryptate-NH2 labeling reagent

Flag Check kit

FLAG check kit standard

GST check kit

GST check kit standard

HTRF cIAP1 BIR2 Binding Kit

HTRF cIAP1 BIR2 Binding Kit - Standard

HTRF cIAP1 BIR3 Binding Kit

HTRF cIAP1 BIR3 Binding Kit - Standard

HTRF Human RIG-I Binding Kit

HTRF Human RIG-I Binding Kit Standard

HTRF Human VHL Binding Kit

HTRF Human VHL Binding Kit Standard

HTRF LCL161 - Red Ligand

HTRF MDM2 Binding Kit

HTRF MDM2 Binding Kit - Standard

HTRF MI-1061 Red Ligand

HTRF PROTAC Binding Buffer 1 - 200mL

HTRF PROTAC Binding Buffer 2-220mL

HTRF PROTAC Binding Buffer 3-220mL

HTRF Strep-Tactin®-d2

HTRF Strep-Tactin®-Eu cryptate

HTRF Strep-Tactin®-Tb cryptate

HTRF Strep-Tactin®-XL665